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However, significant differences between the four DOACs in terms of pharmacokinetic and safety profile are observed and must be considered to personalize the therapy

doi:10.1016/j.brainresbull.2009.06.016

doi: 10.1016/j.biopha.2016.12.044

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It has been established experimentally using X-ray diffraction of the solid fullerene that C 60 contains two unique C-C Bonds (the shorter (6, 6) bonds having values in the range of 1.40 : 1.42 and the longer (5, 6) Bonds measuring 1.45 : 1.46 ) 39 , confirming that the theoretical methods used to perform this study produce the same C structure that has been reported in the literature, thereby validating the methods employed to characterize C 60